Our edge comes from our deep experience and understanding of chemistry and technology.
Flow Chemistry
We are experts in flow chemistry with deep experience of when it will make a difference. Our automated flow reactors can efficiently assess reaction conditions for the optimal result and can be used with solution and solid phase reagents and telescoped reactions.
Microfluidics
We also use microfluidic chips, with their miniaturised low dispersion environment, to optimise and control reactions where control of concentration and stoichiometry are crucial to success. Due to their small internal volume many experiments can be performed on milligrams of material.
Organometallic Chemistry
Flow chemistry can be used to successfully run reactions involving organometallics at higher temperatures than the equivalent batch reaction as well as separating reactive species generation and reaction. We have also pioneered the use of high concentration BuLi with in-situ dilution to improve chemistry outcomes.
Flow Biotransformation
Flow biotransformation with immobilised enzymes can give advantages in lifetime of the support matrix and turn-over numbers. New Path are experts in immobilisation and enzyme reactor and process design.
Gas Liquid Flow Reactions
Our bespoke flow gas reactor is designed to enable trickle bed conditions, decoupling gas concentration from pressure, to give safer, more effective reaction.
Flow Peptide Synthesis
New Path co-developed a unique, patented flow peptide synthesiser with our partners Vapourtec. Separation of activation and coupling and on-line analytics enables the synthesis of challenging peptides including macrocyclic natural products, lanthipeptides and toxins.
Flow Electro- and Photo-chemistry
As part of our close connection with the group of Prof Steve Ley and Vapourtec Ltd we can offer expertise in both flow electrochemistry and flow photochemistry which have wide application in the expansion of chemical space for novel molecule discovery.